Troy Trumble, DVM, PhD, MS

• Orthopedic Surgery and Lameness, including fracture repair and arthroscopic surgery

My research focuses on the translational study of the onset and progression of osteoarthritis. My long-term research goal is to use biomarkers of osteoarthritis as a means to establish early diagnosis of osteoarthritis and identify therapies that will slow its progression. Biomarkers are metabolic by-products of either newly formed or recently broken down components of the joint. They can be measured in joint fluid, blood and/or urine. I have also combined this technology with clinical measures of how horses bear weight when they have osteoarthritis. This is done via the use of a force plate. Results that can be obtained combining these types of clinical and bench-top research can be used to help animals and humans with osteoarthritis.

• “Medical genetics of equine muscle and orthopedic disease.” Co- PI. Funding Source: Minnesota Agricultural Experiment Station
• “Biomarker response to acute joint injury in an animal model of osteoarthritis.” PI. Funding Source: NIH/NIAMS 1R15AR059612-01
• “Biomarker changes using an equine model.” PI. Funding Source: Graduate School, University of Minnesota
• “A pilot study into the effects of intra-articular triamcinolone acetonide on post fetlock arthroscopy kinetic, kinematic, and serum, urine, and synovial fluid biomarker concentrations.” PI. Funding Source: Minnesota Racing Commission, University of Minnesota Equine Center
• “Qualitative and quantitative compensatory effects of lameness in both single and multiple limbs in horses.” PI. Funding Source: Minnesota Racing Commission, University of Minnesota Equine Center

Selected publications

• PubMed
• Google Scholar